America's first appointed woman missionary kept a journal recording her experiences in a multi-ethnic, multi-lingual, religiously pluralistic world. Charlotte Atlee White Rowe's 1815-1822 journal recounts her cross-cultural work among Hindus, Muslims, Eurasians, and Europeans in British India. Most of her entries come from her first years and reveal a ministry being shaped by experience and reflection. Charlotte's picture of life along the Hooghly and Ganges rivers includes temple ceremonies, funeral pyres, child marriage, palanquins, food, climate, snakes, schools, clothing and the lack thereof. She observes colleagues like William Carey working in settings impacted by both the Indian caste and the British class systems. While some entries were intended for the public, her journal was also her private diary. In it she confided intimate thoughts and challenges unique to a woman missionary at the start of the modern missionary movement. Revealing that gender bias had delayed her from acting on her call to ministry for nine years, Charlotte's entries contain nuanced thoughts on gender, women in ministry, and the liberation of girls and women through education. They reveal a strong woman in dialogue with herself and God while remaining confident about her call to public ministry. This newly located journal was unavailable to previous researchers and this transcription preserves the journal's original character. Annotations identify people, places, and events, offer context regarding British India, and define archaic vocabulary. An introduction and conclusion sketch her life before and after India. It is a remarkable addition to mission, women's, and Baptist studies.